products: Rotexmedica-Panpharma - Thiopental Sodium

Name: Thiopental Sodium        500 mg in Glass Vial
 

Thiopental does not usually produce excitation and induction of anaesthesia is usually smooth. It has poor muscle relaxant properties and a muscle relaxant must be administered before intubation is attempted. Thiopental also has poor analgesic properties and small does may even lower the pain threshold. Recovery from an induction dose may occur within 10 to 30 minutes although drowsiness may persist for some time.

In anaesthesia, the dosage of thiopental varies greatly according to the state of the patient and the nature of other drugs being used concurrently. Thiopental is usually administered intravenously as the sodium salt as a 2.5% solution but a 5% solution is occasionally used.

A typical dose for inducing anaesthesia is 100 to 150 mg injected over 10 to 15 seconds, repeated after 30 to 60 seconds according to response. Some prefer to initiate induction with a test dose of 25 to 75 mg. The UK manufacturer recommends that the total dosage used in pregnant patients should not exceed 250 mg. Children's doses range from 2 to 7 mg per kg body-weight.

When thiopental is used as the sole anaesthetic, anaesthesia can be maintained by repeat doses as needed or by continuous intravenous infusion of a 0.2 or 0.4% solution.

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