products: Rotexmedica-Panpharma - Hydrocortisone Sodium Succinate

Name: Hydrocortisone        8 ml Vial

Presentation: White, freeze dried powder of Hydrocortisone sodium succinate for injection, equivalent to 100 mg supplied in rubber –capped vials.

Dosage: Hydrocortisone Sodium Succinate For Injection may be administered by intravenous injection, by intravenous infusion or by intramusular injection, the preferred method for initial emergency use being intravenous injection. Following the initial emergency period, consideration should be given to employing a longer - acting injectable preparation or an oral preparation.

Dosage usually ranges from 100 mg to 500 mg depending on the condition, administered by intranenous injection over a period of one to ten minutes. This dose may be repeated at intervals of 2, 4 or 6 hours as indicated by the patient's response and clinical condition.

Inb general, high - dose corticosteroid therapy should be continued only until the patient's condition has stablised - usually not beyond 48 to 72 hours. If hydrocortisone therapy must be continued beyond 48 to 72 hours hypernaemia may occur. Therefore, it may be preferable to replace Hydrocortisone Sodium Succinate For Injection with a corticosteriod such as methylprednisolone Sodium Succinate as little or no sodium retention occurs. Although adverse effects associated with high dose, short - term corticoid therapy are uncommon, peptic ulceration may occur. Prophylactic antacid therapy may be indicated. Patients subjected to serve stress following corticoid therapy should be observed closely for signs and symptoms of adenocortical insufficiency.

Corticosteroid therapy is an adjunct to and not a replacement for, conventional therapy.

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