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products: Serum Institute of India- Diphtheria & Tetanus Vaccine


Name: Diphtheria and Tetanus Vaccine, Adsorbed for adults and adolescents

Form: Mono dose ampoule 0.5 ml or 10 doses vials 5 ml

Description: Diphtheria and tetanus vaccine adsorbed for adults and adolescents (Td) is prepared by combining purified diphtheria toxoid and purified tetanus toxoid. The antigens are adsorbed onto Aluminium Phosphate as adjuvant. Thiomersal is added as preservative. The vaccine has the appearance of a greyish - white suspension and does not contain any horse serum protein. Therefore, it does not induce sensitization to sera of equine origin. The vaccine meets the requirements of WHO and B.P. when tested by the methods outlined in WHO; TRS. (1990), 800 and B.P.

Potency:
Each single 0.5 ml human dose contains
Diphtheria Toxoid 5 Lf ( 2 IU)
Tetanus Toxoid 5 Lf ( 40 IU)
Adsorbed on Aluminium Phosphate (AlPO4) 1.5 mg
Preservative : 0.01% Thiomersal

Indications: For primary vaccination and revaccination of adults and adolescents, who are having contraindications of DTP.
Primary vaccination and revaccination of children older than 7 years. In order to prevent allergic reactions to the protein of Diphtheria toxoid, the quantity of the toxoid has been markedly reduced.
After a primary immunisation course of either DTP or Td, adsorbed Td for adults may be used as a booster at intervals of approximately 10 years, but with a minimum of at least one year between doses. It can safely replace monovalent tetanus toxoid (TT) vaccine, including during pregnancy.
The vaccine can be safely and effectively given simultaneously with BCG, Measles, Polio Vaccine (IPV and OPV), Hepatitis B and Yellow fever vaccine, Haemophilus influenzae-B and Varicella vaccine.

 

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